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Estrogens, Fractionated by LCMS
Alternate Names: Estrogen Fractions/Fractionated, Estrogen, Estrogens, Estrogens, Serum Fractionated, High sensitivity, Total Estrogens, Estrone (E1) and Estradiols (E2), Ultrasensitive

Test Code	ESTRO
CPT Code	82671
Methodology	Liquid Chromatography/Tandem Mass Spectrometry
Test Includes	Estrone, Serum; Estradiol; Estrogen

Testing Performed	3-4x per week
Reported	Within 2-7 day(s)

Testing Related Disease Topics

Consult Topics.

COLLECTION

Specimen:

Whole Blood

Collection Containers:

Gold top tube (SST)

Alternative Containers

Collection Amounts:

Preferred	4.0 mL
Minimum	2.0 mL

PROCESSING

Specimen Processing Instructions:

Allow specimen to clot 20-30 minutes, centrifuge, and IMMEDIATELY separate serum into transport tube. Contact with gel for > 2 hours should be avoided.

Processing Specimens:

Serum

Processing Containers:

Transfer Tube(s)

Processed Amounts:

Preferred	2.0 mL
Minimum	0.7 mL

SHIPPING/TRANSPORT AND STORAGE

Stabilities/Storage:
(Collection to initiation of testing)

Temperature	Stability
Ambient	1 day(s)
Refrigerated	1 week(s)
Frozen	1 month(s)

Shipping Instructions:

Ship refrigerated.

Reference Ranges

Reference Range Information:

Test	Age	Female	Male
Total Estrogens, Calculation	18 Years and Older	Pre-menopausal: Early Follicular: 30.0-250.0 pg/mL Late Follicular: 200.0-650.0 pg/mL Luteal: 50.0-350.0 pg/mL Post-menopausal: 5.0-52.0 pg/mL	19.0-69.0 pg/mL
	7-9 years	1.0-48.0 pg/mL	< 10.0 pg/mL
	10-12 years	2.0-116.0 pg/mL	1.0-19.0 pg/mL
	13-15 years	15.0-333.0 pg/mL	3.0-62.0 pg/mL
	16-17 years	6.0-354.0 pg/mL	4.0-64.0 pg/mL
	Tanner Stage I	1.0-86.0 pg/mL	1.0-11.0 pg/mL
	Tanner Stage II	3.0-169.0 pg/mL	1.0-19.0 pg/mL
	Tanner Stage III	23.0-351.0 pg/mL	3.0-61.0 pg/mL
	Tanner Stage IV-V	8.0-341.0 pg/mL	4.0-62.0 pg/mL
Estradiol	18 Years and Older	Pre-menopausal: Early Follicular: 30.0-100.0 pg/mL Late Follicular: 100.0-400.0 pg/mL Luteal: 50.0-150.0 pg/mL Post-menopausal: 2.0-21.0 pg/mL	10.0-42.0 pg/mL
	7-9 years	< 36.0 pg/mL	< 7.0 pg/mL
	10-12 years	1.0-87.0 pg/mL	< 11.0 pg/mL
	13-15 years	9.0-249.0 pg/mL	1.0-36.0 pg/mL
	16-17 years	2.0-266.0 pg/mL	3.0-34.0 pg/mL
	Tanner Stage I	< 56.0 pg/mL	< 8.0 pg/mL
	Tanner Stage II	2.0-133.0 pg/mL	< 10.0 pg/mL
	Tanner Stage III	12.0-277.0 pg/mL	1.0-35.0 pg/mL
	Tanner Stage IV-V	2.0-266.0 pg/mL	3.0-35.0 pg/mL
Estrone	18 Years and Older	Pre-menopausal: Early Follicular: < 150.0 pg/mL Late Follicular: 100.0-250.0 pg/mL Luteal: < 200.0 pg/mL Post-menopausal: 3.0-32.0 pg/mL	9.0-36.0 pg/mL
	7-9 years	< 20.0 pg/mL	< 7.0 pg/mL
	10-12 years	1.0-40.0 pg/mL	< 11.0 pg/mL
	13-15 years	8.0-105.0 pg/mL	1.0-30.0 pg/mL
	16-17 years	4.0-133.0 pg/mL	1.0-32.0 pg/mL
	Tanner Stage I	< 27.0 pg/mL	< 7.0 pg/mL
	Tanner Stage II	1.0-39.0 pg/mL	< 11.0 pg/mL
	Tanner Stage III	8.0-117.0 pg/mL	1.0-31.0 pg/mL
	Tanner Stage IV-V	4.0-109.0 pg/mL	2.0-30.0 pg/mL

Estrogens, Fractionated by LCMS Alternate Names: Estrogen Fractions/Fractionated, Estrogen, Estrogens, Estrogens, Serum Fractionated, High sensitivity, Total Estrogens, Estrone (E1) and Estradiols (E2), Ultrasensitive

COLLECTION

PROCESSING

SHIPPING/TRANSPORT AND STORAGE

Reference Ranges

Estrogens, Fractionated by LCMS
Alternate Names: Estrogen Fractions/Fractionated, Estrogen, Estrogens, Estrogens, Serum Fractionated, High sensitivity, Total Estrogens, Estrone (E1) and Estradiols (E2), Ultrasensitive